NAD +

Nicotinamide Adenine Dinucleotide (NAD+) is an essential coenzyme found in all living cells. It plays a critical role in cellular metabolism, mitochondrial function, energy production (ATP synthesis), DNA repair, and the regulation of sirtuins (proteins associated with cellular aging and longevity).
As endogenous NAD+ levels decline with age, metabolic stress, and chronic inflammation, exogenous supplementation via intravenous (IV) infusion or subcutaneous (SubQ) injection is utilized to restore cellular viability. 

NAD+ Intravenous (IV) Infusions

IV administration delivers NAD+ directly into the systemic circulation, bypassing the gastrointestinal tract for 100% bioavailability.

• Primary Indications:
  • Systemic cellular rejuvenation and anti-aging support.
  • Chronic fatigue syndrome and mitochondrial dysfunction.
  • Cognitive enhancement (mitigating "brain fog" and supporting neuroprotection).
  • Adjunctive therapy for addiction recovery and detoxification (helps restore neurotransmitter balance and reduce cravings).
• Administration Protocol:
  • Requires a slow, controlled intravenous drip (typically over 2 to 4 hours, depending on the dose, which ranges from 250 mg to 1000 mg).
• Side Effects & Tolerability:
  • Rapid infusion can cause transient, dose-dependent side effects due to rapid cellular uptake. These include chest tightness, physiological flushing, mild abdominal cramping, nausea, headache, and localized vascular pressure.
  • Slowing the infusion rate immediately mitigates these symptoms.

NAD+ Subcutaneous (SubQ) Injections

Subcutaneous injection involves administering smaller doses of NAD+ into the adipose tissue (typically the abdomen or thigh) for gradual absorption.

• Primary Indications:
  • Maintenance of NAD+ levels between IV sessions.
  • Convenient, ongoing support for metabolic rate, physical energy, and cognitive function.
• Administration Protocol:
  • Typically self-administered or clinic-administered 1 to 3 times per week using a small-gauge insulin syringe. Doses are significantly lower than IV infusions (typically 25 mg to 100 mg per injection).
• Side Effects & Tolerability:
  • Well-tolerated with minimal systemic side effects.
  • Localized injection site reactions (mild burning, redness, or soreness) are common but transient.